Berikut ini adalah sub keahlian bidang informatika di Universitas Sains Indonesia :

Computer Network, Architecture and High Performance Computing
1. Indonesia Cyber Defense Framework
2. Next Generation Networking
3. Wireless Sensor Network
4. Odor Source Localization, Swarm Robot
5. Traffic Signal Control System
6. Autonomous Telecommunication Networks
7. Smart Cardio Device
8. Smart Ultrasonography for Telehealth
9. Smart Home System
10. Grid/High Performance Computing, etc

Information Retrieval
1. Data Mining
2. Computational Linguistics
3. Natural Language Processing
– Named Entity Recognition
– Information Extraction
– Creative Text Reconstruction
4. Information Retrieval – Text
– Multimedia
– Peer to Peer and Social Media Analysis
5. Plagiarism Detection, etc

Reliable So­ftware Engineering
1. Discrete Mathematics
2. Theorem Prover
3. Program Refinement
4. Model Checker
5. Graph Mining
6. Soft­ware Quality Assurance
7. Program Verification
8. Soft­ware Correctness and Reliability
9. Security Protocol
10. Computational Logic
11. Soft­ware Testing and Testbed Generator

Digital Library & Distance Learning
1. Digital Library
2. Online and Distance Learning
3. Multichannel Access
4. Cloud Technology
5. OER (Open Educational Resource)
6. Semantic Web Technology
7. Cognitive Systems and Self-Regulated Learning
8. Interaction Design, Usability, and User Experience, etc

E-Government & E Business
1. e-Commerce
2. IT Government
3. IT Plan
4. Corporate Resource Management
5. Supply Chain Management, etc

Machine Learning & Computer Vision
1. e-Health (multi-lab )
2. Parallel Processing
3. Biomedic
4. Remote Sensing
5. Intelligent Multimedia Information Processing
6. Agriculture, e-Livestock
7. Precise Farming
8. Twitter Sentiment Analysis
9. Social Robotic, etc

Information Management
1. Enterprise Architecture
2. Business/IT Alignment
3. IS/IT Strategic Planning
4. IS/IT Benet Management
5. IS/IT Governance
6. IT Service Management
7. IT Adoption & User Acceptance
8. IT Project Management
9. IT Risk/Security Management
10. Decision Analytic & Support
11. Knowledge Management, etc